A new ray of hope has been shown in the direction of resolving problems with eyes with age. Scientists have succeeded in rejuvenating the rat’s eyes with the help of gene therapy. This breakthrough in the initial stage can open the way for the treatment of many age-related eye diseases in humans. This research has been published in the science journal Nature.
Scientists said that this is the first time that complex tissues such as nerve cells have been safely reprogrammed and taken to the capacity of puberty. David Sinclair, a genetics professor at Harvard Medical School in the US, said, “Our study has revealed that the age of a complex tissue such as the retina can be reversed and its potential can be elevated to the level of puberty.”
During the experiment, scientists have also been able to overcome such a disease in mice, which has a lot of glaucoma-like symptoms. Glaucoma is the leading cause of blindness worldwide. Scientists say that not only in the case of eye light but with the successful use of this experiment, it may be possible to cure many symptoms related to age in humans and to get treatment for diseases.
This is how the experiment
During the experiment, scientists sent three such genes to the retina of the rat, which was able to bring the ability of the retina to the level of puberty. Adeno associated virus (AAV) was used to deliver the gene to the retina. Scientists reported that these three genes OCT4, SOX2, and KLF4 are usually activated at the time of fetal development. During this experiment, it was also successful to bring back the rat’s eyesight.